Verapamil
Verapamil
- In our pharmacy, you can buy Verapamil with a prescription, available online and in local pharmacies.
- Verapamil is used for the treatment of hypertension, angina pectoris, and supraventricular arrhythmias. It works as a calcium channel blocker, inhibiting the influx of calcium ions into cardiac and smooth muscle cells.
- The usual dosage of Verapamil is 80-120 mg taken orally three times daily, with a maximum daily dose of up to 480 mg.
- The form of administration is a tablet or intravenous solution.
- The effect of the medication begins within 30-60 minutes for oral dosing and within minutes for intravenous administration.
- The duration of action is up to 24 hours for sustained-release formulations.
- Alcohol should be consumed with caution as it may increase the risk of side effects.
- The most common side effect is constipation.
- Would you like to try Verapamil without a prescription?
Basic Verapamil Information
• INN (International Nonproprietary Name): Verapamil
• Brand names available in Canada: Calan, Verelan, Tarka
• ATC Code: C08DA01
• Forms & dosages: 40 mg, 80 mg, 120 mg tablets
• Manufacturers in Canada: Abbott, Pfizer, Mylan, Sandoz, Teva
• Registration status in Canada: Rx (Prescription only)
International Nonproprietary Name (Inn)
Verapamil is the International Nonproprietary Name (INN) for a specific calcium channel blocker. This medication primarily helps manage conditions related to the cardiovascular system. It’s crucial for patients to know the INN as this name is universally recognized and is often used in clinical settings for safety and accuracy in prescribing.
Brand Names in Canada
In Canada, verapamil is commonly available under the brand name **Calan**, offered in tablet forms of **40 mg, 80 mg, and 120 mg**. This brand name is consistent with its availability in the United States. Moreover, internationally, **Verelan** and **Tarka** are recognized forms, typically available as **120 mg and 180 mg extended-release capsules**. Each of these formulations is designed to reduce the frequency of dosing while maintaining therapeutic effectiveness, making it easier for patients to adhere to their medication schedules.
Atc Code
Verapamil is classified under the **ATC Code C08DA01**, which identifies it as a calcium channel blocker. This classification indicates its primary function of inhibiting calcium influx across cell membranes, particularly in heart and vascular smooth muscle. It’s categorized as part of the **Class IV antiarrhythmics**, according to the Vaughan Williams classification system. Understanding this classification helps healthcare professionals determine its utility across various cardiovascular conditions.
Manufacturers and Registration Status
In Canada, verapamil is produced by well-known manufacturers such as **Abbott, Pfizer, Mylan, Sandoz, and Teva**. These companies ensure that the drug meets regulatory standards, enhancing both safety and efficacy. Currently, verapamil is available as a prescription-only medication in Canada, meaning it requires a healthcare provider's authorization for dispensing. This classification helps monitor its distribution and use, ensuring it’s administered safely and effectively to those who need it.
Medication Forms
Verapamil is available in various forms to accommodate patient preferences and specific medical needs. The most common form includes:
- Tablets: Available in strengths of **40 mg, 80 mg, and 120 mg**.
- Extended-release capsules: Typically found as **120 mg and 180 mg** variants.
- Intravenous solutions: Often used in acute care settings, available at **2.5 mg/mL**.
Dosage & Administration
Understanding the right dosage of Verapamil is crucial for effective treatment. Here’s a quick breakdown:
| Indication | Initial Dose | Max Daily Dose |
|---|---|---|
| Hypertension | 80-120 mg PO 3 times daily | Up to 480 mg/day |
| Angina Pectoris | 80-120 mg PO 3 times daily | Up to 480 mg/day |
| Arrhythmias (SVT) | 120-240 mg (SR) 1-2 times daily | 480 mg/day |
It’s important to consider dosing adjustments based on individual patient factors. Special caution is needed for the elderly or those with renal or hepatic impairment, as adjustments may be necessary.
When it comes to storing Verapamil, keep it in a cool, dry place, ideally between 15-30°C. Protect it from moisture and light to maintain its effectiveness.
Safety & Warnings
Safety is a top priority when using Verapamil. Certain conditions serve as absolute contraindications, meaning Verapamil should not be used if:
- Severe hypotension is present.
- There is a second or third-degree AV block.
- Severe heart failure exists.
- There is a known allergy to Verapamil.
Common side effects include:
- Constipation
- Dizziness
- Headache
More severe side effects involve hypotension and bradycardia, which require immediate attention.
Be particularly cautious if pregnant or if there are liver or kidney issues, as careful monitoring is essential in these cases.
Patient Experience
Feedback from users shows a mixed bag of results with Verapamil, particularly regarding its effectiveness for treating hypertension and angina. Many patients have shared their experiences on platforms like Drugs.com and WebMD.
A significant number of users report side effects, especially constipation, which can lead to challenges with adherence to treatment. It's a common concern and can hinder the effectiveness of therapy.
Community forums echo similar sentiments, emphasizing the importance of open communication with healthcare providers. Patients find reassurance and better outcomes when they actively discuss their experiences and adjustments to treatment plans.
Alternatives & Comparison
When considering alternatives to Verapamil in Canada, two significant options stand out: Diltiazem and Amlodipine. Both medications are used to manage hypertension and heart-related conditions, offering various benefits and side effects that may suit different patients.
| Alternative | Price | Effectiveness | Safety | Availability |
|---|---|---|---|---|
| Diltiazem | $XX | High | Moderate | Widely available |
| Amlodipine | $XX | High | Low | Commonly prescribed |
Local physicians often prefer one alternative over the other based on factors such as individual patient responses or specific health conditions. For instance, a patient with a history of poor tolerance to certain medication classes may be better suited to one of these alternatives over Verapamil. Understanding these nuances can significantly affect treatment outcomes.
Market Overview
In Canadian pharmacies, Verapamil can be easily found at major chains such as Shoppers Drug Mart and Rexall.
Pricing is variable, typically ranging from $XX to $YY, depending on the formulation and specific pharmacy location.
Verapamil is packaged in various forms, including blisters, bottles, and sachets, making it user-friendly. Each manufacturer may offer different branding on the packaging.
Demand patterns reveal that this medication is often used chronically by patients dealing with hypertension and arrhythmias. Interestingly, some patients even utilize it seasonally for migraine management.
Research & Trends
Recent studies and meta-analyses from 2022 to 2025 indicate an expanding efficacy for Off-label uses, particularly in migraine prevention, which has piqued interest among healthcare providers.
Future research is currently directed toward ongoing trials that explore additional cardiovascular conditions and potential benefits within metabolic syndromes, promising to widen the indications for Verapamil.
As patents for branded formulations have expired, the market has seen a surge in generic alternatives, allowing for more accessible treatment options.
Guidelines for Proper Use
When taking Verapamil, the recommendation is to ingest it with food or water for optimal absorption. It’s essential to align with your healthcare provider's specific timing recommendations.
To maximize effectiveness:
- Avoid alcohol and high-calcium foods; they may interfere with the medication.
- Regularly consult with your healthcare provider about interactions with other prescriptions.
Store Verapamil in a cool, dry place away from light to maintain its effectiveness. Patients should be cautious of common mistakes such as doubling doses and should communicate any side effects to their healthcare team immediately.
Finally, always consult the patient information leaflet that accompanies the medication for precise instructions and ensure to seek professional advice whenever unsure.