Uniphyl Cr

Uniphyl Cr

Dosage
400mg
Package
360 pill 180 pill 120 pill 90 pill 60 pill 30 pill
Total price: 0.0
  • In our pharmacy, you can buy Uniphyl Cr without a prescription, with delivery in 5–14 days throughout the US. Discreet and anonymous packaging.
  • Uniphyl Cr is intended for the treatment of chronic asthma and COPD. The drug acts as a bronchodilator by relaxing the muscles around the airways.
  • The usual dosage of Uniphyl Cr for adults is 300 mg–600 mg per day, typically taken once daily or divided into two doses.
  • The form of administration is an extended-release tablet.
  • The effect of the medication begins within 30–60 minutes.
  • The duration of action is approximately 12 hours.
  • Do not consume alcohol while taking this medication.
  • The most common side effect is nausea.
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Uniphyl Cr

Basic Uniphyl Cr Information

  • INN (International Nonproprietary Name): Theophylline
  • Brand names available in Canada: Uniphyl, Theo-24, Elixophyllin, Theolair
  • ATC Code: R03DA04
  • Forms & dosages: Extended-release tablets (100 mg, 200 mg, 250 mg, 300 mg, 400 mg, 450 mg, 600 mg); Oral solution (80 mg/15 mL)
  • Manufacturers in Canada: Medicis (US)
  • Registration status in Canada: Generally registered as prescription (Rx) only
  • OTC / Rx classification: Prescription only

Understanding Theophylline: A Key Medication

Theophylline serves as a crucial medication primarily for asthma and chronic obstructive pulmonary disease (COPD). In Canada, it is marketed under several brand names, including **Uniphyl**, **Theo-24**, **Elixophyllin**, and **Theolair**. Each formulation caters to different patient needs, typically aimed at relaxing the airway muscles to ease breathing difficulties. Additionally, it has the **ATC Code** R03DA04, classifying it among bronchodilator agents known as xanthines. This classification is important for healthcare providers and patients alike, helping them understand the function and purpose of the drug. For those interested in the specifics, Theophylline comes in multiple **dosage forms and strengths**. Extended-release tablets are available in concentrations from **100 mg to 600 mg**. There is also an **oral solution** form at a concentration of **80 mg per 15 mL**, making it easier for individuals to find a format that suits their needs. Manufactured primarily by **Medicis** in the US, the medication typically requires a prescription in Canada. It's worth noting that Theophylline has received approval from health authorities like the FDA and EMA for its efficacy in treating asthma and COPD.

How Theophylline Works in The Body

Understanding the pharmacology behind Theophylline sheds light on why it is effective. At a cellular level, theophylline works primarily by relaxing the muscles around the airways. This mechanism helps clear out mucus and opens up the air passages, making it easier to breathe. The onset of action for Theophylline is usually observed within a few hours of administration. Its effects can last up to 12 hours. This sustained action is particularly beneficial for adults and children who need stable control of their asthma symptoms or COPD. When it comes to metabolism and elimination, Theophylline is processed in the liver and then excreted via the kidneys. The half-life of Theophylline varies but is crucial for determining dosing frequency. For many, this means **startup dosing** may be higher, while maintenance dosages can adjust based on individual response and tolerability. However, be cautious about interactions. Theophylline can engage in significant interactions with various medications, including **antibiotics**, and even substances like **caffeine** and **alcohol**. This interference can either decrease its effectiveness or increase the risk of side effects, making it essential to discuss all medications you’re taking with your healthcare provider.

Approved Indications for Theophylline

The primary indications for Theophylline include its role as an effective treatment for asthma and COPD. Both the FDA and EMA have recognized its efficacy for these conditions, signifying robust clinical support. Interestingly, Theophylline is sometimes used off-label in Canada for other airway conditions, such as **chronic bronchitis**. This flexibility highlights its importance in managing various respiratory issues. For unique populations, dosing guidelines exist: - **Pediatrics:** Dosages are typically based on weight, ensuring children receive the correct amount. - **Elderly:** Careful monitoring and adjustments are essential; older adults may experience varying sensitivities. Pregnant women should consult their healthcare practitioners, as the pharmacologic effects and safety can vary greatly in this group. This understanding of Theophylline demonstrates its role as a multifaceted medication addressing the needs of different patients while underlining the importance of proper dosing and monitoring.

Dosage & Administration of Uniphyl

Managing dosages effectively can mean the difference between relief and discomfort for patients. Understanding how to use Uniphyl, a popular form of theophylline, is crucial.

For adults, the typical dosage ranges from 300 mg to 600 mg daily, often starting at 400 mg. Pediatric dosages are more individualized, calculated based on weight, usually between 10 mg to 13 mg/kg/day.

Adjustments are critical for individuals with comorbidities. For those with liver or renal impairments, dosage titration is essential. Using Uniphyl in these cases demands caution, as metabolism may significantly differ.

Proper storage and transport are vital to preserving the medication's efficacy. Uniphyl should be kept at room temperature between 20–25°C (68–77°F), and it can withstand 15–30°C (59–86°F) during transport. Ensure it remains in a dry, tightly closed container, away from excessive heat and moisture. Following these guidelines can help maintain the integrity of the medication.

Safety & Warnings for Uniphyl

Awareness of safety concerns is a top priority when prescribing or using Uniphyl. Contraindications must be taken seriously: allergies to xanthines, recent myocardial infarctions, and certain seizure disorders make using this medication unsuitable.

Side effects can range from common to rare. Some people report:

  • Mild nausea and vomiting
  • Headache and heartburn
  • Restlessness and insomnia

More severe effects can manifest as palpitations, tremors, or increased urination. Patients need to be aware of these potential outcomes to ensure they are monitoring their response closely.

Special precautions should be taken during pregnancy. While the risks versus benefits should be considered, it’s essential for individuals with liver or kidney issues to approach dosage carefully. Black box warnings may also apply, particularly regarding potential liver toxicity.

Patient Experience with Uniphyl

User reviews on platforms like Drugs.com and Reddit provide valuable insight into the effectiveness and tolerability of Uniphyl. Many users note significant improvements in asthma symptoms, appreciating its extended-release formulation.

In community forums like Facebook groups, testimonials emphasize the medication’s impact on daily life, with some sharing experiences of side effects that forced adjustments in dosage. For instance, users have reported needing to balance the benefits against issues like insomnia or gastrointestinal upset.

Nevertheless, challenges in adherence are common. Some patients express difficulty remembering to take their dosage at the same time each day, a necessity for maintaining blood levels. Understanding these experiences can guide healthcare providers in offering more tailored support, whether through reminders or education on the medication's importance.

Alternatives & Comparison to Uniphyl

For individuals seeking alternatives to Uniphyl in Canada, options include Aminophylline and Beta-agonists such as salbutamol. These alternatives can provide similar bronchodilation benefits but may vary in efficacy and side effects.

Medication Price Effectiveness Safety Profile
Aminophylline Moderate Effective Generally safe
Salbutamol Low Very effective Well-tolerated

Local physicians often express preferences based on patient familiarity and specific needs. Some may lean toward inhalers for acute episodes, while others prefer the stable dosing that extended-release options like Uniphyl provide. Ultimately, individual treatment plans should cater to each patient’s unique requirements while balancing efficacy with comfort.

Market Overview (Canada)

Where can you find Uniphyl in Canada? It's stocked in various pharmacies like Catena and HelpNet, making it quite accessible for those needing this medication. Uniphyl, containing Theophylline, is popular among patients managing chronic respiratory conditions.

Price-wise, you can expect the typical Uniphyl price in Canada to range from $30 to $90, depending on the dosage and the pharmacy. These prices may fluctuate, so it's wise to compare options before purchase.

When it comes to packaging, Uniphyl is often found in extended-release tablet forms of 300 mg and 400 mg, either in blister packs or bottles. This ensures that the medication is both easy to use and convenient for daily management.

Demand for Uniphyl tends to follow patterns tied to chronic conditions, particularly asthma and COPD. Seasonal spikes often occur during flu season when more patients experience exacerbated respiratory symptoms. Understanding these trends can be beneficial for pharmacies in managing stock effectively.

Research & Trends

Recent studies from 2022 to 2025 have shed light on Theophylline's efficacy and usage. Notably, meta-analyses have demonstrated its effectiveness for patients with moderate to severe asthma, leading to renewed interest in this long-established medication. Researchers are also exploring experimental uses of Theophylline, including its potential application in combination therapies for various respiratory conditions.

In terms of generics, Theophylline is expected to remain available as companies market generic versions of Uniphyl. This is particularly important for long-term affordability for Canadian patients. As for its patent status, the original patent has expired, paving the way for more competition in the market and potentially lowering prices for consumers.

Guidelines for Proper Use

Taking Uniphyl properly can make a significant difference in managing symptoms. It's advisable to take the medication at the same time every day, with water and either with or without food—just find what works best for you. However, avoid alcohol, as it can interfere with how the medication works.

Storing Uniphyl is quite straightforward; keep it at room temperature in a dry place. Avoid exposing the tablets to excess moisture or heat to maintain their efficacy. Monitoring your dosing schedule is key, so be cautious of common mistakes like taking double doses if you forget one. If you miss a dose, just take it as soon as you remember, but skip it if it's nearly time for the next dose.

It's also essential for patients to read the patient leaflet that comes with the medication. Consulting healthcare providers can provide tailored advice based on individual health needs. This helps ensure that you're using Uniphyl safely and effectively.