Basic Revatio Information

• INN (International Nonproprietary Name)
• Brand names available in Canada
• ATC Code
• Forms & dosages (e.g., tablets, injections, creams)
• Manufacturers in Canada
• Registration status in Canada
• OTC / Rx classification

International Nonproprietary Name (Inn)

The International Nonproprietary Name for Revatio is Sildenafil. The use of INNs allows for consistency across prescriptions and helps healthcare professionals globally recognize medications. This uniformity is crucial, as it avoids confusion that may arise from varied brand names and ensures that patients receive the correct medication regardless of locale.

Atc Code

Revatio is classified under the ATC code G04BE03. This categorization highlights its function as a *Urological* drug aimed explicitly at treating erectile dysfunction. More specifically, it belongs to a class of medications known as *Phosphodiesterase-5 (PDE5) inhibitors*, which play a vital role in facilitating increased blood flow to various parts of the body.

Brand Names in Canada

In Canada, the primary brand name for Sildenafil is Revatio, available in 20 mg tablets and as an oral powder. The brand is manufactured by Pfizer, a well-recognized pharmaceutical company, known for its extensive product profiles and commitment to quality across various jurisdictions.

Dosage Forms

Dosage Form	Form Details
Tablets	Round, white, 20 mg
Oral Powder	For suspension, 10 mg/mL (reconstituted)
Injectable	IV solution (10 mg/12.5 mL vial)

Rx Classification

Revatio is classified as a prescription only (Rx) medication. This classification emphasizes the importance of proper clinical oversight, ensuring that patients receive guidance on usage, dosage, and potential interactions with other medications. The regulation helps maintain patient safety, as Sildenafil can have serious health implications if taken improperly or without appropriate medical advice.

Dosage & Administration of Revatio

Understanding the correct Revatio dosage can make all the difference when managing pulmonary arterial hypertension (PAH). For adults, the standard dosage is 20 mg taken three times a day. Pediatric dosages are usually weight-adjusted, allowing for safe administration based on individual needs.

When it comes to special populations, adjustments may be necessary. Children can use oral suspension or 20 mg tablets, taken three times daily. The elderly may require careful attention to how they respond to the medication, as they might exhibit increased sensitivity. Individuals with liver or kidney issues are advised to consult healthcare professionals since dosage adjustments may be important for safety.

Treatment for PAH generally requires an indefinite duration, as it's a chronic condition that needs ongoing management. Storing Revatio properly is crucial; keep it at room temperature between 20-25°C and away from moisture.

For transporting, ensure any IV solutions are protected from moisture, as well as adhering to specific holding limits to maintain efficacy.

Safety & Warnings for Revatio

Safety with Revatio is paramount, and understanding its contraindications is crucial for effective usage. Absolute contraindications include concurrent use of nitrates, as this can lead to severe hypotension. Those with significant liver or renal issues should be assessed closely when considering Revatio.

Common side effects include headaches and flushing, while rare side effects can include priapism and severe vision changes. Severe side effects may manifest as symptoms linked to heart attack or severe hypotension. The following table summarizes common, rare, and severe side effects:

Side Effect Type	Examples
Common	Headaches, flushing
Rare	Priapism, severe vision changes
Severe	Heart attack symptoms, hypotension

Special precautions should be taken for those who are pregnant or suffering from pre-existing liver or kidney conditions. Additionally, while there are no black box warnings currently, ongoing studies continue to assess long-term safety.

Patient Experience with Revatio

Hearing from others can provide insight into using Revatio. Feedback from sources such as Drugs.com and Reddit highlights a mix of experiences. Users often describe Revatio as effective for managing PAH, but some raise concerns about side effects.

In English forums on Facebook and TPU, users share both positive and negative insights. Many highlight the positive impact on their quality of life while managing PAH. Conversely, some mention challenges with side effects like headaches and flushing, which can be bothersome.

Personal stories often reveal the emotional toll of adhering to medication. For instance, some patients feel overwhelmed by the regimen and the fear of side effects but are grateful for the improvement in their health condition. Overall, understanding the collective sentiments of users can foster a supportive community around medication adherence.

Common Alternatives in Canada

When it comes to alternatives to Revatio, patients often consider other medications that target similar conditions. Two notable competitors are Tadalafil and Bosentan. - **Tadalafil** works by inhibiting the enzyme phosphodiesterase type 5 (PDE5), enhancing blood flow by relaxing blood vessels. It's known for a longer duration of action, making it a popular choice for those managing pulmonary arterial hypertension (PAH). - **Bosentan**, on the other hand, is an endothelin receptor antagonist that helps lower blood pressure in the pulmonary arteries. By blocking the effects of endothelin, a substance that constricts blood vessels, it effectively improves exercise capacity in patients with PAH. - Lastly, **Riociguat** works by stimulating soluble guanylate cyclase, leading to vasodilation and improved blood flow. This newer medication is effective for both PAH and chronic thromboembolic pulmonary hypertension, making it a valuable option in treatment.

Table of Comparisons

Understanding the differences between these medications can help in making informed decisions.

Drug	Price (CAD)	Effectiveness	Safety Profile	Availability
Tadalafil	$XX	Similar	Generally safe	Pharmacies A, B
Bosentan	$XX	Effective	Monitoring needed	Pharmacies C

Local Doctor Preferences

Insights from healthcare professionals reveal how they approach prescribing medications for various patient profiles. For patients with specific comorbidities, doctors might prefer Tadalafil over Revatio due to its longer duration of efficacy. In instances where close monitoring is feasible, Bosentan is a frequent choice for those with more extensive pulmonary complications. Doctors often tailor their recommendations based on individual responses, potential side effects, and the specific health conditions of their patients. By weighing the pros and cons, they aim to find the most effective treatments while focusing on patient safety. Navigating medication options can feel overwhelming, but understanding these alternatives can empower patients to have informed discussions with their healthcare providers.