Parlodel

Parlodel

Dosage
2,5mg
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  • In our pharmacy, you can buy Parlodel without a prescription, with delivery available in many countries worldwide. Discreet and anonymous packaging.
  • Parlodel is used for the treatment of hyperprolactinemia, Parkinson’s disease, and acromegaly. The drug is a dopamine D2 agonist that suppresses prolactin and growth hormone levels.
  • The usual dosage of Parlodel varies by condition, typically starting at 1.25–2.5 mg for hyperprolactinemia and up to 2.5 mg for Parkinson’s disease.
  • The form of administration is a tablet.
  • The effect of the medication generally begins within 1–2 hours after ingestion.
  • The duration of action is typically 8–12 hours.
  • It is advised to avoid alcohol while taking Parlodel as it may increase the risk of side effects.
  • The most common side effect is nausea, which is dose-dependent.
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Basic Parlodel Information

  • INN (International Nonproprietary Name): Bromocriptine
  • Brand names available in Canada: Parlodel, Parlodel Sandoz, Bromocriptin-ratiopharm, Cycloset
  • ATC Code: G02CB01
  • Forms & dosages: Tablets (commonly 2.5 mg, rare 5 mg)
  • Manufacturers in Canada: Novartis Pharma/Novartis Sandoz, generics from Ratiopharm, Teva, Zentiva
  • Registration status in Canada: Rx only
  • OTC / Rx classification: Prescription medication

Understanding Bromocriptine

Bromocriptine is a medication with a wide array of applications, primarily functioning as a prolactin inhibitor. Here’s a quick overview: - **International Nonproprietary Name (INN):** Bromocriptine is recognized globally under this standard name. - **Brand Names in Canada:** The most notable brand available in the Canadian market is **Parlodel**. Other options include: - **Parlodel Sandoz**: This is a generic alternative produced by Sandoz, primarily found in Europe. - **Bromocriptin-ratiopharm**: Available in Germany. - **Cycloset**: Utilized in the United States for diabetes management. - **Classification:** Bromocriptine is classified under the ATC Code **G02CB01**, denoting its role as an ergot derivative that inhibits prolactin production. - **Forms and Dosages:** The medication is typically available in tablet form, with 2.5 mg as the standard dose, although a rarer 5 mg formulation can also be found. - **Manufacturers:** The global originator is **Novartis Pharma/Novartis Sandoz**. Additionally, generics are available from manufacturers such as **Ratiopharm, Teva,** and **Zentiva**. - **Registration Status:** Bromocriptine holds a global approval for various medical uses; however, it is primarily prescribed in Canada and other markets. Understanding the foundational elements of bromocriptine is essential for anyone considering this medication or seeking further information about its uses and availability.

Pharmaceutical Context of Bromocriptine

With several applications in the medical field, bromocriptine proves to be a versatile therapy. Those interested should consult healthcare providers for personalized advice regarding dosage and potential effects. For detailed guidance on how bromocriptine works and who it is appropriate for, reliable sources such as Health Canada can provide invaluable information.

Dosage & Administration of Parlodel

Understanding how to use Parlodel effectively can significantly impact treatment outcomes. Here’s a breakdown of typical dosages based on various conditions:

Condition Starting Dose Typical Maintenance Max Dose
Hyperprolactinemia 1.25 mg–2.5 mg qd/bid Up to 7.5 mg/day 15 mg/day
Acromegaly 1.25–2.5 mg qd/bid Gradual titration, up to 20 mg/day 30 mg/day
Parkinson's Disease 1.25 mg qd/bid, adjust as needed 10–40 mg/day Rarely 100 mg/day

When it comes to age and reno-hepatic health, adjustments are crucial:

  • For elderly patients, starting at a lower dose is key and closer monitoring is advised.
  • Caution should be exercised in those with hepatic or renal impairment.

The treatment duration is dependent on the condition being treated. For hyperprolactinemia, long-term use is common, along with routine checks of prolactin levels. Storage is straightforward; keep Parlodel at room temperature and shield it from light.

Safety & Warnings for Parlodel

Safety is paramount when it comes to using Parlodel. Awareness of potential contraindications can help prevent serious complications. Here's a quick overview:

Contraindications

  • Absolute: Uncontrolled hypertension, severe psychiatric disorders, known hypersensitivity to bromocriptine.
  • Relative: Cardiovascular disease, hepatic or renal impairment, history of peptic ulcers.

Side Effects

Side Effects Severity
Nausea Common, dose-dependent
Dizziness Very common in starters
Fatigue Frequent reports
Severe confusion/hallucinations Rare, e.g., among the elderly or those on high doses

Special precautions need to be taken during pregnancy. Use should be cautiously avoided unless critically necessary. Dosing should be adjusted and monitored closely in patients with liver or kidney impairment. Currently, there are no black box warnings associated with this medication.

Patient Experience with Parlodel

User reviews on platforms such as Drugs.com and Reddit offer valuable insights into real-life experiences with Parlodel.

User Feedback

  • Effectiveness: Many users report significant relief from symptoms of hyperprolactinemia and improvements in Parkinson's management.
  • Side Effects: Common complaints include nausea and fatigue, which are often manageable.

Additionally, stories from other forums reflect unique insights, particularly regarding adherence challenges and overall satisfaction with their treatment plans. It's important to note that effectiveness can vary among individuals, so any discrepancies should be discussed with healthcare providers.

Common Alternatives in Canada

When considering options for bromocriptine, several alternatives are available in Canada that serve similar purposes. Each has its own unique attributes. Understanding these alternatives might help in making informed decisions.

Compound Trade Names Use
Cabergoline Dostinex Hyperprolactinemia
Quinagolide Norprolac Hyperprolactinemia
Pergolide (withdrawn) Parkinson’s (limited)

Comparison of Parlodel and Its Alternatives

Grasping the differences among these medications can shed light on their effectiveness, availability, and safety. The table below offers a clear view of what to expect from each drug:

Drug Price (CAD) Effectiveness Safety Availability
Parlodel XX.XX Established Standard monitoring Widely available
Cabergoline YY.YY More effective, less frequent dosing Lower side effect profile Moderate availability

Preferences Among Local Doctors

Among healthcare professionals, cabergoline has gained traction. The preferences stem from a few key points:

  • Less frequent dosing makes it convenient for patients.
  • Lower side effect rates enhance patient compliance and satisfaction.
  • Established efficacy for treating hyperprolactinemia compared to older alternatives.

In the realm of medication alternatives, local doctors often prioritize patient comfort and adherence, focusing on options like cabergoline when prescribing.