Basic Metronidazole Information

• INN (International Nonproprietary Name)
• Brand names available in Canada
• ATC Code
• Forms & dosages (e.g., tablets, injections, creams)
• Manufacturers in Canada
• Registration status in Canada
• OTC / Rx classification

Understanding Metronidazole: Basic Information

Metronidazole, known as an antibacterial and antiprotozoal medication, is commonly prescribed to treat various infections. In Canada, key brands include Neo-Tric and Trikacide. It's essential to recognize that Metronidazole is a prescription-only medication primarily due to its potential for resistance and adverse effects. This means that individuals must obtain a prescription from a healthcare provider to access it.

ATC Classification and Available Forms

Metronidazole's ATC code is J01XD01, categorized under antibacterials for systemic use. You'll find this medication available in multiple forms, including:

• Tablets
• Injectable solutions
• Topical creams and gels

Manufacturers and Product Registration

In Canada, several manufacturers produce Metronidazole, including major players like Pfizer and Teva. The medication enjoys wide recognition and approval from regulatory bodies like the FDA in the United States and the EMA within Europe. Patients should note its classification as a prescription-only medication to understand the implications of usage and access.

Overall, careful consideration is essential when using Metronidazole, given its role in effectively treating infections while minimizing the risk of resistance.

D) Dosage & Administration

Dosage guidelines for Metronidazole vary based on the condition being treated. For instance:

• Anaerobic infections: 500 mg either intravenously (IV) or orally every 8 hours.
• Trichomoniasis: A single dose of 2 grams or 250 mg three times daily for 7 days.
• Bacterial vaginosis: 500 mg taken twice daily or a topical application of 0.75% for 5–7 days.
• Amoebiasis/giardiasis: 500–750 mg three times daily for 5–10 days.
• Rosacea: Apply topical cream or gel twice daily for several weeks.

Adjustments are essential for specific populations. Elderly patients should be monitored closely for possible side effects, as increased susceptibility is common. Those with liver impairment may need a dose reduction, particularly in severe cases.

Typical treatment durations range from 3 to 14 days, depending on the severity and type of infection. Proper storage is crucial: keep tablets, capsules, and creams at room temperature (15–25°C). IV solutions should be shielded from light to maintain their efficacy, without the need for refrigeration.

E) Safety & Warnings

Metronidazole has both absolute and relative contraindications that users must be aware of. Absolute contraindications include documented allergies to Metronidazole or other nitroimidazoles, and its use during the first trimester of pregnancy should be avoided unless absolutely necessary.

Relative contraindications include:

• Active central nervous system (CNS) disorders, such as epilepsy.
• Severe liver disease, which may require additional monitoring.
• Chronic alcohol use due to the potential for disulfiram-like reactions when conjunctioned with alcohol.

Common side effects include nausea, a metallic taste, headaches, and dizziness, while rarer severe reactions may involve neurological symptoms. Caution is advised in special populations, including those with liver disease or seizure disorders. Black box warnings are not typically associated with Metronidazole, but vigilance is crucial.

F) Patient Experience

When examining user reviews, sentiments on platforms like Drugs.com and WebMD highlight a mix of effectiveness and manageable side effects. Many users report positive outcomes when treating infections effectively.

In community forums such as Reddit and Facebook groups, patient experiences vary widely, with some sharing successfully navigating side effects while others encountered issues. Anecdotes illustrate that medication adherence can vary based on individual circumstances, leading to differing perceptions of effectiveness.

One common theme in user feedback is the importance of clear communication with healthcare providers, as this greatly influences adherence rates and overall satisfaction.

G) Alternatives & Comparison

In Canada, several alternatives to Metronidazole are commonly used, including Tinidazole and Clindamycin. Here’s how they stack up:

Local physicians often have preferences depending on patient history and the specific infection being treated. Understanding these choices might help guide discussions with healthcare providers about alternatives.

Market Overview of Metronidazole

When seeking Metronidazole, many wonder where to find it and how much it costs. Pharmacies like Catena and HelpNet generally stock this medication. Ordering can often be done through local pharmacies, or online platforms may also carry it, facilitating easy access.

The average price of Metronidazole varies by formulation. Generally, expect to pay between 10 to 30 CAD for a standard course of treatment, depending on the package and dosage strength. For those side-eyeing the packaging, you’ll find Metronidazole comes in various forms, from blister packs to convenient bottles and even gels for topical applications. This variety ensures that patients can choose the form that suits their needs better.

Demand patterns for Metronidazole reveal interesting insights. There’s a consistent demand for this medication due to chronic conditions like bacterial infections and certain gastrointestinal diseases. Seasonal spikes can occur, especially in colder months, as respiratory infections increase. Understanding these demand patterns is key for both patients and healthcare providers