Lithobid

Lithobid

Dosage
300mg
Package
360 pill 180 pill 120 pill 90 pill 60 pill 30 pill
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  • In our pharmacy, you can buy Lithobid with a prescription, available in the Canada and globally in packages of 100-500 extended-release tablets of 300 mg.
  • Lithobid is used for the acute treatment of manic episodes in bipolar disorder and maintenance therapy to reduce the frequency and severity of these episodes. It acts by stabilizing mood through its effects on neurotransmitters in the brain.
  • The usual dosage for adults is 600 mg/day to start, with adjustments made based on serum levels; maintenance dosages typically range from 900–1200 mg/day.
  • The form of administration is an extended-release tablet, which should be swallowed whole.
  • The onset time for Lithium can vary, but it generally takes 1-3 weeks to notice symptom control.
  • The duration of action is 24 hours for extended-release formulations.
  • Avoid alcohol as it can exacerbate the side effects associated with Lithium.
  • The most common side effect is tremor, which can be dose-related.
  • Would you like to try Lithobid without a prescription?
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Basic Lithobid Information

  • INN (International Nonproprietary Name)
  • Brand names available in Canada
  • ATC Code
  • Forms & dosages (e.g., tablets, injections, creams)
  • Manufacturers in Canada
  • Registration status in Canada
  • OTC / Rx classification

INN (Generic Name) Definition and Importance

Lithium Carbonate is a crucial medication in psychiatric treatment, primarily used for managing bipolar disorder. It operates as a mood stabilizer, playing a vital role in reducing the frequency and intensity of manic episodes. The effectiveness of lithium on mood swings makes it a preferred choice for many healthcare providers. Given its narrow therapeutic index, careful monitoring is essential to avoid toxicity while achieving the desired therapeutic effects.

Brand Names in Canada

In Canada, Lithium Carbonate is marketed under several brand names. The most prominent include:
- **Carbolith**: Available in varying strengths of tablets (150 mg, 300 mg, and 450 mg).
- **Lithane**: Offered in capsules and tablets, mainly generic in nature.
These brand names, along with generic options of lithium carbonate, ensure accessibility for patients across the country.

ATC Code Classification

The ATC code for Lithium Carbonate is **N05AN01**. This classification falls under the psycholeptics category, specifically within antipsychotics. Understanding the ATC classification helps healthcare providers determine the medication's therapeutic use, safety, and efficacy in treating mental health conditions.

Dosage Forms Available

Lithium Carbonate is available in various dosage forms, suitable for patient needs. These include:
- **Extended-release tablets** (300 mg): Taken whole, this option is designed for stable, prolonged absorption throughout the day.
- **Immediate-release tablets and capsules**: Found in strengths of 150 mg, 300 mg, and 450 mg, providing flexibility in dosing.
- **Oral solution**: Available as an 8 mEq/5mL formulation, this form is used for more precise dosing adjustments, especially beneficial in pediatric populations.
These diverse forms ensure that patients can find a suitable option that meets their treatment requirements.

Manufacturers in Canada

Key manufacturers of Lithium Carbonate in Canada include AbbVie, known for its brand Lithobid, and various generic sources. Generic pharmaceutical companies such as Amneal, Sun Pharma, and Teva also play a significant role in making this essential medication available to Canadian patients. It's crucial for healthcare providers and patients to be aware of these manufacturers to ensure they receive high-quality medication.

Registration Status

Health Canada regulates Lithium Carbonate as a prescription-only medication. Both Carbolith and Lithane are licensed for usage in Canada, ensuring that they meet the required safety and efficacy standards. Additionally, in comparison, the European Union also has registered Lithium Carbonate, marking it safe for use across different jurisdictions.

OTC/Rx Classification

Lithobid is classified strictly as a prescription medication throughout all regions. This classification underlines the importance of professional guidance when initiating or adjusting treatment, given the potential side effects and the need for monitoring. Patients looking to obtain Lithobid or other lithium carbonate formulations should consult their healthcare providers to ensure proper use and oversight.

Dosage & Administration of Lithobid

The way Lithobid is dosed can vary depending on the condition being treated. For adults facing acute mania, the typical starting dosage is around 600 mg per day, often delivered in two extended-release tablets of 300 mg each. As treatment progresses, dosages may be adjusted based on individual serum lithium levels, with a maintenance dose ranging from 900 to 1200 mg per day.

In children aged seven and older, the starting dose should be calculated as 15 to 20 mg per kilogram of body weight per day, which should then be carefully adjusted based on ongoing monitoring. Elders require special attention, often starting at a reduced dose of 150 to 300 mg per day due to altered renal function and increased sensitivity to lithium’s effects.

For individuals with renal impairment, the initial dosage must be lowered, and close monitoring of serum lithium levels is crucial to avoid toxicity risks. Treatment for both acute manic episodes generally lasts from one to three weeks, while maintenance therapy may extend for years or even a lifetime.

Store Lithobid at room temperature, ideally between 20-25°C, in a moisture-free environment to maintain its effectiveness. Avoid keeping the medication in bathrooms. Always use the original container for transport to safeguard its integrity.

Safety & Warnings for Lithobid

There are several critical contraindications to keep in mind when prescribing Lithobid. Absolute contraindications include severe renal impairment, known hypersensitivity to lithium, uncontrolled hypothyroidism, and significant cardiovascular disease. In pregnant women, especially during the first trimester, caution is advised due to potential teratogenic effects.

Relative contraindications involve mild to moderate renal impairment, where dose adjustment and monitoring are essential. Special care should also be taken with the elderly and those experiencing dehydration, sodium imbalance, or using concurrent medications like diuretics and NSAIDs.

The side effects associated with Lithobid range from common to severe. Mild effects often include tremors, thirst, nausea, and gastrointestinal upset, usually manageable with supportive care. Severe reactions may involve lithium toxicity, which necessitates immediate medical treatment. It's critical for pregnant women or those with renal disease to follow guidelines closely.

A black box warning is in effect due to the potential risks in vulnerable populations. Understanding these guidelines is essential for responsible prescribing and patient safety.

Patient Experience with Lithobid

When examining reviews from sources such as Drugs.com and Reddit, many patients report that Lithobid is effective for stabilizing moods in bipolar disorder. Users appreciate its role in managing manic episodes but often mention the side effects, particularly tremors and increased thirst, which impact daily life.

Insights from Canadian health forums reveal common themes regarding adherence challenges. Many users express difficulty maintaining the dosage schedule while balancing other medications and responsibilities. Some have found community support helpful, sharing coping strategies for side effects and the importance of consistent blood monitoring.

Though some patients initially struggled with side effects, many noted that they became more manageable over time. Adherence issues often stem from concerns about the medication's effects rather than its effectiveness. This suggestive feedback is vital for healthcare providers to consider in treatment plans, ensuring they address both efficacy and patient comfort.

Alternatives & Comparison of Bipolar Disorder Medications in Canada

Patients often wonder about the alternatives to Lithobid when managing bipolar disorder. There are several effective medications that can fit different needs, such as:

  • Carbamazepine: Used for mood stabilization and typically offers quick relief during manic episodes.
  • Valproic Acid: Known for its efficacy in mood swings, especially in mixed episodes.
  • Lamotrigine: Primarily used as a maintenance therapy to prevent mood episodes.

These alternatives come with varying effectiveness, side effects, and costs.

Medication Average Price (CAD) Safety Profile Effectiveness
Carbamazepine $25/month Moderate Effective for mania
Valproic Acid $30/month Moderate Effective for mixed episodes
Lamotrigine $45/month High Effective for maintenance

Why might doctors opt for one medication over another? Factors like patient history, specific symptoms, and tolerance to side effects heavily influence their choices.

Market Overview of Lithobid in Canada

Finding Lithobid in Canada is generally straightforward. It's often available at local pharmacies such as Catena, along with major chains across provinces. This accessibility ensures that patients can easily obtain their prescriptions.

Pricing tends to vary, averaging around $40 for a month's supply, though costs can shift based on provincial health coverage and local market conditions. In general, larger communities see slightly lower prices due to competition.

Packaging formats also differ. Most commonly, Lithobid comes in child-resistant amber bottles containing extended-release tablets, ensuring safety and efficacy. There are also blister packs available in some regions, making it easier to manage dosing.

When it comes to demand patterns, there's noticeable variability. Seasonal changes and patient management cycles may lead to fluctuations in prescriptions, particularly during times of heightened stress in chronic populations.

Recent Research & Trends Related to Lithium

Recent meta-analyses published between 2022 and 2025 have reinforced the effectiveness of Lithium in treating acute manic episodes and preventing relapses. These studies continue to highlight its importance as a first-line treatment for bipolar disorder.

Exciting experimental research has surfaced regarding the potential neuroprotective effects of Lithium. It's being explored for conditions beyond bipolar disorder, such as neurodegenerative diseases.

As for the patent status, Lithium carbonate, including Lithobid, has transitioned into generic alternatives, allowing for broader patient access. This is particularly significant as the patents for some branded versions expire, promoting affordability and competition.