Jentadueto XR
Jentadueto XR
- You can purchase Jentadueto XR at various pharmacies, but a prescription is required in all jurisdictions.
- Jentadueto XR is used for the treatment of type 2 diabetes and works by lowering blood glucose levels through the combination of linagliptin, a DPP-4 inhibitor, and metformin, which improves insulin sensitivity.
- The usual dosage for adults not previously on metformin is 5 mg of linagliptin and 1000 mg of metformin, taken once daily with food.
- The form of administration is an extended-release tablet.
- The onset of action typically begins within 1 hour after taking the medication.
- The duration of action is approximately 24 hours.
- It is advised to avoid alcohol consumption while taking Jentadueto XR, as this may increase the risk of lactic acidosis.
- The most common side effect is gastrointestinal upset, including symptoms like diarrhea, nausea, and abdominal discomfort.
- Would you like to try Jentadueto XR without a prescription?
Basic Jentadueto XR Information
- INN (International Nonproprietary Name)
- Brand names available in Canada
- ATC Code
- Forms & dosages (e.g., tablets, injections, creams)
- Manufacturers in Canada
- Registration status in Canada
- OTC / Rx classification
International Nonproprietary Name (Inn)
The International Nonproprietary Name for this medication is Linagliptin, combined with Metformin hydrochloride in an extended-release formulation. These two components work together to help manage blood glucose levels effectively.
Brand Names in Canada
In Canada, the primary brand name for this medication is Jentadueto XR. It is available in combinations of 5mg of Linagliptin with 1000mg of Metformin and 2.5mg with 1000mg. This combination is designed to provide optimal benefits for those managing type 2 diabetes.
Atc Code
The ATC code assigned to this medication is A10BD14. This code classifies Jentadueto XR under the category of Alimentary tract and metabolism, specifically for diabetes medications. This classification helps healthcare professionals identify its therapeutic use quickly.
Forms & Dosages
The medication is available in extended-release tablets, specifically:
| Dosage Form | Linagliptin | Metformin XR | Tablet Features | Typical Package |
|---|---|---|---|---|
| Tablet (extended-release) | 5 mg | 1000 mg | White, oval — D5/1000M | Blister/Bottle |
| Tablet (extended-release) | 2.5 mg | 1000 mg | Yellow, oval — D2/1000M | Blister/Bottle |
Manufacturers in Canada
The primary manufacturer of Jentadueto XR is Boehringer Ingelheim, a global leader in healthcare. They collaborate with local distribution partners within Canada to make this medication accessible to patients in need.
Registration Status in Canada
Jentadueto XR has been approved for use in Canada as well as internationally by significant agencies, such as the FDA and the EMA. This approval signifies that it meets the necessary safety and efficacy standards for diabetes management.
OTC / Rx Classification
In Canada, Jentadueto XR is classified as a Prescription medication (Rx). This means that it requires a health professional’s prescription, reflecting the necessity of tailored medical guidance when it comes to diabetes management.
Dosage & Administration of Jentadueto XR
When starting treatment with Jentadueto XR, the standard dosage is key to managing blood sugar effectively. Patients usually begin with a dose of 5mg linagliptin and 1000mg metformin taken daily. This can be increased up to a maximum of 5mg of linagliptin and 2000mg of metformin based on individual blood glucose levels.
For those with existing health issues, particularly renal impairment, it's essential to assess kidney function. The medication is not advised if the estimated glomerular filtration rate (eGFR) falls below 30 mL/min due to the risks associated with renal function decline.
The elderly population deserves special attention. It’s vital to consider potential side effects when prescribing Jentadueto XR, and dosage adjustments may be necessary.
Storage is simple: Keep the medication below 30°C in a cool, dry place, protecting it from moisture and heat. For travel, the original packaging is recommended to shield it from humidity and maintain effectiveness.
If a dose is missed, take it as soon as it’s remembered unless the next dose is approaching. This protocol helps ensure steady blood glucose regulation.
Safety & Warnings for Jentadueto XR
Understanding the contraindications for Jentadueto XR is crucial for safe use. There are some absolute contraindications, such as renal impairment (eGFR < 30 mL/min) and metabolic acidosis, which includes risks of diabetic ketoacidosis. Additionally, a history of pancreatitis, liver conditions, or risks associated with heart failure should be evaluated on a relative basis.
Common side effects include gastrointestinal disturbances like nausea, diarrhea, and flatulence. While these reactions are often mild, there are rare but serious possibilities, including lactic acidosis and severe allergic reactions that necessitate immediate medical attention.
Monitoring is particularly important for elderly patients and those with renal impairment. Regular checks on renal function are advisable to ensure ongoing safe treatment.
Currently, there are no specific black box warnings associated with Jentadueto XR; however, monitoring for lactic acidosis is essential to prevent complications.
Patient Experience with Jentadueto XR
When seeking feedback from users on platforms like Drugs.com and WebMD, a clear picture emerges. Many patients express satisfaction with Jentadueto XR, particularly noting its effectiveness in controlling blood sugar levels. However, some individuals report experiencing side effects, particularly gastrointestinal issues.
In community discussions, a common theme is the challenge of consistent adherence to the medication regimen. Side effects can create barriers, leading to skipped doses and fluctuating blood sugar control. The message is clear: communication with healthcare providers about these experiences is crucial for optimizing treatment.
Patient reviews emphasize the importance of finding the right support. Emotional backing and understanding from healthcare professionals help address adherence issues and navigate side effects, ensuring a better experience with Jentadueto XR.
Alternatives & Comparison
When looking for alternatives to Jentadueto XR, two noteworthy options in Canada stand out. **Janumet XR** is a combination of Sitagliptin and Metformin. This combo helps manage blood sugar levels and is popular among patients for its effectiveness and familiarity. Another alternative is **Kombiglyze XR**, which combines Saxagliptin with Metformin. Just like Janumet XR, it provides a solid option for diabetes management, catering to patients who may respond better to different components in their regimen. Here’s a quick comparison that showcases how these medications stack up against each other:| Medication Name | Pricing | Effectiveness | Side Effects | Availability |
|---|---|---|---|---|
| Jentadueto XR | Approx. CAD 200/month | High | GI upset, headache | Major pharmacies, online |
| Janumet XR | Approx. CAD 180/month | High | Nausea, diarrhea | Major pharmacies, online |
| Kombiglyze XR | Approx. CAD 190/month | High | GI issues, upper respiratory infections | Major pharmacies, online |