Basic Information about Glycomet

INN (International Nonproprietary Name)	Brand Names in Canada	ATC Code	Forms and Dosages	Manufacturers in Canada	Registration Status in Canada	OTC / RX Classification
Metformin	Glycomet, Glucophage	A10BA02	Tablets (500 mg, 850 mg, 1000 mg)	Apotex, Teva Canada	Prescription drug	Prescription only

Glycomet, known generically as Metformin, is an oral antidiabetic medication used primarily in the treatment of type 2 diabetes. It helps control blood sugar levels by decreasing glucose production in the liver and improving insulin sensitivity. In Canada, Glycomet is marketed under several brand names, including Glucophage, and is registered with the ATC code A10BA02. Available in various dosages, including 500 mg, 850 mg, and 1000 mg tablets, it is manufactured by reputable pharmaceutical companies such as Apotex and Teva Canada. Glycomet is classified as a prescription-only medication, requiring medical supervision due to possible interactions and side effects.

Dosage and Administration of Glycomet

The dosage of Glycomet depends on the patient's blood glucose levels and response to treatment. Typical starting doses are 500 mg once or twice daily with meals, with gradual titration up to a maximum of 2000–2550 mg/day, depending on patient tolerance.

• Initial dose: 500 mg once or twice daily
• Maintenance dose: Up to 2000 mg per day, divided into 2–3 doses
• Maximum dose: Usually 2550 mg/day

It is important to take Glycomet with food to minimize gastrointestinal discomfort. Elderly patients and those with kidney or liver dysfunction require closer monitoring and possible dose adjustments.

Safety and Warnings of Glycomet

Glycomet should not be used in individuals with:

• Severe kidney impairment (eGFR <30 mL/min/1.73 m²)
• Acute or chronic metabolic acidosis, including diabetic ketoacidosis

Common side effects include gastrointestinal issues such as nausea, diarrhea, and abdominal discomfort. Rare but serious side effects include lactic acidosis, which is potentially life-threatening. Special caution is advised during pregnancy, surgery, or use of iodinated contrast agents. Always consult a healthcare provider before making any changes to medication.

Patient Experience with Glycomet

Many patients report positive results in controlling blood glucose levels, especially when combined with proper diet and exercise. Online platforms such as Drugs.com and CanadianDiabetesAssociation.ca provide reviews highlighting improved energy levels and reduced complications from hyperglycemia. However, some users report initial gastrointestinal discomfort. These symptoms typically subside after the first few weeks of consistent use.

Alternatives and Comparisons to Glycomet

Common alternatives to Metformin in Canada include:

• Gliclazide – Used for similar glycemic control, often in patients intolerant to Metformin
• Sitagliptin – A DPP-4 inhibitor, used in combination therapy
• Empagliflozin – An SGLT2 inhibitor, also helps in weight loss

Drug Name	Price	Efficacy	Safety	Availability
Gliclazide	$$	High	Moderate	Prescription
Sitagliptin	$$$	High	High	Prescription
Empagliflozin	$$$	High	High	Prescription

Market Overview in Canada

In Canada, Glycomet and other Metformin-based products are widely prescribed and covered under most provincial healthcare plans. The price for a month's supply ranges from CAD 10 to CAD 40, depending on the brand and pharmacy. Demand remains consistent year-round due to the chronic nature of type 2 diabetes. Generic versions are widely available and offer an affordable solution for long-term therapy.

Recent Research and Trends

Recent studies (2022–2025) have explored Metformin's potential benefits beyond diabetes, including anti-aging effects, cancer risk reduction, and cardiovascular protection. Its off-label uses and continued research interest ensure Glycomet remains at the forefront of diabetic care in Canada.

Frequently Asked Questions

Q: Can I take Glycomet with other diabetes medications?
A: Yes, it is often combined with other oral agents or insulin. Your doctor will determine the right combination. Q: Does Glycomet cause weight loss?
A: Some patients experience mild weight loss, especially when combined with dietary changes. Q: Is Glycomet safe long-term?
A: Yes, it's widely considered safe for long-term use under regular medical supervision.