Eskalith
Eskalith
- Eskalith can be purchased through pharmacies with a prescription, as it is a prescription-only medication.
- Eskalith is used for the treatment of acute mania and maintenance in bipolar disorder. It helps stabilize mood by modulating neurotransmitter release in the brain.
- The usual dosage of Eskalith for acute mania is 600–900 mg per day in 2–3 divided doses, while the maintenance dosage for bipolar disorder is 600–1200 mg per day.
- The form of administration is capsules or tablets.
- The effect of the medication typically begins within 1-3 weeks, depending on the individual’s response and dosage adjustments.
- The duration of action is approximately 24 hours, necessitating multiple daily doses for sustained effect.
- Alcohol consumption is not recommended while taking Eskalith, as it may enhance side effects and toxicity.
- The most common side effect is fine tremor.
- Would you like to try Eskalith without a prescription?
Eskalith
Basic Eskalith Information
- INN (International Nonproprietary Name)
- Brand names available in Canada
- ATC Code
- Forms & dosages (e.g., tablets, injections, creams)
- Manufacturers in Canada
- Registration status in Canada
- OTC / Rx classification
Understanding Eskalith and Lithium Carbonate
The International Nonproprietary Name, or INN, for Eskalith is lithium carbonate. This compound is commonly used as a mood stabilizer, particularly in treating bipolar disorder. In some European listings, lithium carbonate may be referred to as "Lithiumum carbonicum."
Brand Names Used in Canada
In Canada, Eskalith is available in various formulations including the standard Eskalith and Eskalith-CR (controlled-release) versions. The packaging options commonly include:
| Brand Name | Dosage Forms | Strengths |
|---|---|---|
| Eskalith | Capsules | 300 mg |
| Eskalith-CR | Controlled-Release Tablets | 450 mg |
| Generic Lithium Carbonate | Available in Capsules/Tablets and Oral Solutions | 150 mg, 300 mg, 600 mg |
Classification and ATC Code
Eskalith has an ATC code of N05AN01, indicating its classification as a psycholeptic, specifically used as an antimanic agent. This signifies that lithium carbonate is part of a group of medications used to affect mood and behaviour.
Forms and Dosages
Lithium carbonate is available in multiple forms, making it versatile for various treatment options. The common forms include:
| Form | Dosage Strengths |
|---|---|
| Capsule | 150 mg, 300 mg, 600 mg |
| Tablet | 300 mg |
| Controlled-Release Tablet | 450 mg |
| Oral Solution | 300 mg/5 mL |
Manufacturers and Production
Eskalith was originally manufactured by GlaxoSmithKline. However, due to the brand's discontinuation in some regions, a plethora of generic manufacturers now produce lithium carbonate. These include well-known companies such as Sun Pharma, Teva, Lupin, and Sandoz.
Prescription Status and Regulatory Information
In Canada, Eskalith is classified as a Prescription Only (Rx) medication. It is essential for patients to get a prescription from a licensed healthcare provider to ensure proper management of treatment. This medication is particularly monitored due to its narrow therapeutic index, meaning that dosages must be carefully managed to avoid toxicity. Always consult with a healthcare professional or refer to Health Canada's resources for any updated information on the regulatory status of lithium carbonate products.
Dosage & Administration
Understanding proper Eskalith dosing is crucial for effective treatment. Typical dosages vary based on the condition being treated:
- Acute mania: Start with 600–900 mg per day in 2-3 divided doses.
- Maintenance for bipolar disorder: 600–1200 mg daily, adjusted for serum lithium levels between 0.6–1.2 mEq/L.
When it comes to age adjustments, children under the age of 12 should use Eskalith cautiously, and the doses generally must be titrated according to their body weight and serum lithium levels. For the elderly, a lower starting dose (around 150–300 mg/day) is advisable as they are more prone to side effects and toxicity.
Recommended treatment durations typically see acute mania managed until symptoms stabilize, followed by long-term maintenance often extending to years. Always store Eskalith at room temperature, ideally between 20–25°C, away from moisture and heat. It should be kept tightly closed and out of reach of children.
Safety & Warnings
Several contraindications exist when using Eskalith. Absolute contraindications include:
- Severe renal impairment
- Dehydration or sodium depletion
- Known hypersensitivity to lithium
- Significant cardiovascular disease
- Pregnancy and breastfeeding
Relative contraindications requiring close monitoring include heart disease and mild renal impairment.
Side effects can range from mild to severe. Common side effects include:
- Fine tremors
- Mild gastrointestinal upset
- Increased thirst and urination
More severe effects, while rare, can include hypothyroidism or significant tremor. Special precautions are imperative for pregnant women and those with liver or kidney issues, and a black box warning highlights potential toxicity, making regular monitoring essential.
Patient Experience
User reviews from platforms like Drugs.com and Reddit highlight a mixed experience with Eskalith. Many users appreciate its effectiveness in stabilizing mood and reducing manic episodes. However, side effects like tremors and gastrointestinal distress are commonly reported.
Patients often mention adherence challenges due to side effects and the need for regular blood tests to monitor lithium levels. Overall, while Eskalith has been effective for many, the experience varies significantly, emphasizing the importance of communication with healthcare providers.
Alternatives & Comparison
For individuals looking for alternatives to Eskalith, medications like Lithobid and Quilonum are popular in Canada. These options also fall under the category of lithium carbonate but may vary in effectiveness and side effects.
| Medication | Price | Effectiveness | Safety | Availability |
|---|---|---|---|---|
| Eskalith | Moderate | Effective | Requires monitoring | Prescription |
| Lithobid | Moderate | Effective | Requires monitoring | Prescription |
| Quilonum | Varies | Effective | Requires monitoring | Prescription |
Local healthcare providers often have their preferences leaning towards Lithobid due to its ease of use and established efficacy. However, patient response can vary greatly, so a personalized approach is crucial when considering treatment options.
Market Overview of Eskalith
Where can you find Eskalith? It's available at various local pharmacies, including Catena and HelpNet. Patients often turn to these trusted outlets for their prescription needs. Additionally, online pharmacies may also stock Eskalith, but checking local options ensures a quicker access.
What about pricing? The average cost of Eskalith in Canada hovers around $40 to $60 for a month's supply, depending on the dosage and specific pharmacy. Costs may fluctuate based on insurance coverage or discounts available through various programs.
When it comes to packaging, Eskalith typically comes in several forms: 300 mg capsules, 450 mg controlled-release tablets, and sometimes in liquid solutions. This variety allows healthcare providers to tailor treatment options based on patient needs.
Demand for Eskalith has shown notable patterns. Many patients use it chronically for managing bipolar disorder. During the pandemic, there's been a noticeable increase in demand as mental health concerns escalated. This surge highlights the critical role Eskalith plays in supporting those living with severe mood disorders.
Research & Trends Related to Eskalith
Recent studies published between 2022 and 2025 have focused intensely on Eskalith. Notably, significant meta-analyses have confirmed its effectiveness in treating acute mania and stabilizing mood over the long term in bipolar disorder patients. These findings have reinforced the medication's reputation as a gold standard in mood stabilization.
In addition to established uses, some research is evaluating experimental applications for Eskalith, particularly in treatment-resistant depression and anxiety management. These explorations could lead to broader prescribing guidelines in the future, benefiting patients with diverse mental health needs.
What’s the status regarding patents and generics? Initially, Eskalith was branded, but it has since faced discontinuation in some markets, including the United States. Still, generics are readily available, providing a budget-friendly alternative for patients. This accessibility is crucial for ensuring that more individuals can benefit from lithium carbonate therapy.
Guidelines for Proper Use of Eskalith
Wondering when to take Eskalith? It's best taken consistently at the same time every day, preferably during meals to minimize gastrointestinal upset. Patients should always consult their healthcare provider about any additional medications or supplements that might interact with Eskalith.
To ensure effectiveness, avoid coffee, alcohol, and other medications like NSAIDs without discussing it with a doctor first. Hydration is crucial, so staying hydrated will enhance treatment efficacy.
Storage is straightforward. Keep Eskalith at room temperature, away from heat and moisture, and ensure it is stored in a tightly closed container out of children's reach.
A common mistake? Missing doses can hinder treatment benefits. If a dose is missed, take it as soon as possible but skip it if the next dose is approaching. Doubling up is not recommended.
Always follow directions as provided in the patient leaflet and by healthcare professionals. This guidance is vital for safely and effectively managing treatment with Eskalith.
