Colofac
Colofac
- In our pharmacy, you can buy Colofac without a prescription in some EU/UK pharmacies, while it is prescription-only in many other countries including Australia.
- Colofac is intended for the relief of abdominal pain, cramps, and bowel irregularity in irritable bowel syndrome (IBS). The drug is a synthetic anticholinergic that helps alleviate gut spasms.
- The usual dosage of Colofac is 135 mg taken three times daily in tablet form, or 200 mg in modified-release capsule form taken twice daily.
- The form of administration is tablets, modified-release capsules, or oral liquid.
- The effect of the medication begins within 30 minutes to an hour.
- The duration of action is approximately 4 to 6 hours.
- It is advisable to avoid alcohol while taking Colofac, as it may increase side effects.
- The most common side effect is gastrointestinal disturbances such as heartburn and indigestion.
- Would you like to try Colofac without a prescription?
Basic Colofac Information
- INN (International Nonproprietary Name)
- Brand names available in Canada
- ATC Code
- Forms & dosages (e.g., tablets, injections, creams)
- Manufacturers in Canada
- Registration status in Canada
- OTC / Rx classification
INN And Brand Names
The International Nonproprietary Name (INN) for this medication is Mebeverine. In Canada, it is sold under the brand name Colofac®, available in multiple forms including 135 mg tablets, 200 mg modified-release capsules, and oral liquid options for easier consumption.
ATC Code And Dosage Forms
The ATC Code for Colofac is A03AA04. This classification indicates it falls under drugs for functional gastrointestinal disorders, specifically synthetic anticholinergics. Dosage forms available include:
| Form | Strength | Typical Dosing |
|---|---|---|
| Standard tablets | 135 mg | 1 tablet, three times daily |
| Modified-release capsules | 200 mg | 1 capsule, twice daily |
| Oral liquid | Equivalent to tabs | As needed for swallowing difficulties |
Manufacturers
The main producer for Colofac in Canada is Abbott Laboratories, which has merged with Mylan to become part of Viatris. Other manufacturers include well-known companies like Teva and Sanofi, which operate primarily in Europe and Australia.
Registration Status
Colofac is available both as an over-the-counter (OTC) medication as well as a prescription drug in various jurisdictions, with regulations around small versus larger packaged quantities differing from place to place. This provides flexibility for patients seeking symptomatic relief from gastrointestinal issues.
Dosage & Administration of Colofac
When it comes to managing Irritable Bowel Syndrome (IBS), finding the right dosage is crucial. The usual adult dosage for Colofac is straightforward: 135 mg three times daily or a 200 mg modified-release capsule taken twice daily. This allows for effective symptom control for many users.
Adjustments for Age and Comorbidities
Most adults will follow this standard dosage. However, certain factors may require careful consideration. For older adults or those with liver or kidney impairments, there aren’t specific formal adjustments required, but it’s wise to use caution and monitor the patient's response to the medication closely.
Treatment Duration and Storage Guidelines
The duration of Colofac treatment can vary. Patients may find themselves on it for weeks or even months, depending on symptom severity and persistence. It's recommended to revisit healthcare providers if symptoms continue after two weeks to reassess the treatment plan. When it comes to storage, keep Colofac safely in its original packaging, away from moisture, and at a temperature below 25°C for optimal efficacy.
Safety & Warnings for Colofac
Before starting Colofac, be aware of several important safety guidelines. Absolute contraindications include any known hypersensitivity to mebeverine, as well as conditions like paralytic ileus and specific metabolic disorders such as hereditary galactose intolerance.
Common Side Effects
Every medication comes with the potential for side effects. With Colofac, most users report mild effects including headaches and dizziness, as well as moderate gastrointestinal issues like diarrhea and constipation. Serious side effects are rare but can include adverse allergic reactions that should prompt immediate medical attention.
Special Precautions
For those with severe liver or kidney issues, or women who are pregnant, it’s advised to use Colofac with caution. Though data on breastfeeding is limited, avoiding the medication during this period is generally recommended for precautionary reasons.
Patient Experience with Colofac
<pUnderstanding what users are saying about Colofac can help new patients set realistic expectations. Insights from user reviews on platforms like Drugs.com typically reveal a high level of satisfaction, with many finding effective relief from IBS symptoms while experiencing few side effects.Feedback From Forums
<pEngagement in community forums like Reddit and Facebook showcases a notable trend: Many users express a marked preference for Colofac over other antispasmodic medications. One key reason is its potential to cause less sedation, allowing for better daily function.Subjective Insights
<pThat said, patients have shared challenges with adherence to the medication. Issues often stem from cost or the necessity of a prescription. Some users note that the effective relief from symptoms often feels more pronounced with continuous use over time. Gathering insights from peers can be a source of support in navigating treatment options.Alternatives & Comparison for Colofac
When managing gastrointestinal discomfort, understanding alternatives can be crucial. Some common alternatives to Colofac in Canada include:
- Dicyclomine (Bentyl)
- Hyoscine butylbromide (Buscopan)
- Peppermint oil (Colpermin)
Comparison Table of Antispasmodics
| Drug Name | Form | Cost Range (CAD) | Efficacy | Availability |
|---|---|---|---|---|
| Colofac | Tablets, caps | $12 - $30 | High | OTC/Rx |
| Dicyclomine | Caps | $10 - $25 | Moderate | Rx |
| Hyoscine Butylbromide | Tablets | $15 - $35 | Moderate | Rx |
| Peppermint Oil | Capsules | $8 - $20 | Low | OTC |
Doctor Preferences for Colofac
Local practitioners often recommend Colofac for its targeted action, particularly due to the lower risk of sedation compared to other anticholinergics. This preference further emphasizes its safety profile, making it a go-to choice for many addressing gastrointestinal spasms and discomfort.
Market Overview for Colofac in Canada
Understanding where to find Colofac is essential for effective treatment. It is commonly available in major pharmacy chains like Catena and HelpNet, as well as various online platforms. This convenience enhances accessibility for those needing relief.
Average Pricing for Colofac
The average retail price for Colofac ranges from $12 to $30 CAD, depending on the dosage and the retailer. This cost-effectiveness places it as an attractive option for those in need of antispasmodic therapy.
Packaging Details and Demand Patterns
Colofac is offered in blister packs and bottles, designed to protect the contents from light and moisture. Increased demand for this medication has been noted during seasonal gastrointestinal disruptions. Additionally, the rise in chronic conditions post-pandemic has contributed to its growing popularity.
Current Research Trends for Colofac
Clinical trials are currently underway that evaluate the efficacy and safety of Colofac in diverse populations, with a specific focus on long-term effects and gut motility. This ongoing research is expected to further substantiate its role in gastrointestinal treatment.
Experimental Uses of Mebeverine
Recent studies have begun to explore the potential for off-label uses of mebeverine, particularly in conditions like functional dyspepsia and other gastrointestinal disorders. These findings might open doors for broader applications beyond what is typically prescribed.
Patent Expiry and Generics
The current patents surrounding Colofac are nearing expiry, which will likely lead to an influx of generic options in the market. This development is anticipated to enhance competition and provide more affordable options for patients in need of antispasmodic treatment.