Asacol
Asacol
- In our pharmacy, you can buy Asacol with a prescription, available in various markets including the U.S., U.K., and EU.
- Asacol is used for the treatment of ulcerative colitis and works as an intestinal anti-inflammatory agent by delivering mesalazine directly to the colon.
- The usual dosage of Asacol for mild to moderate active ulcerative colitis is 2.4–4.8 g/day, divided into several doses.
- The form of administration is a delayed-release tablet, available in 400 mg and 800 mg strengths.
- The effect of the medication usually begins within 1–2 weeks.
- The duration of action can last for 8 hours, providing significant symptom relief.
- Limit alcohol consumption while using Asacol, as it may increase the risk of side effects.
- The most common side effect is headache, but gastrointestinal issues like nausea or diarrhea may also occur.
- Would you like to try Asacol without a prescription?
Basic Asacol Information
- INN (International Nonproprietary Name)
- Brand names available in Canada
- ATC Code
- Forms & dosages (e.g., tablets, injections, creams)
- Manufacturers in Canada
- Registration status in Canada
- OTC / Rx classification
Understanding Asacol and Mesalazine
The **International Nonproprietary Name (INN)** for the medication widely used in treating inflammatory bowel disease is **Mesalazine**, also known as **Mesalamine** or 5-ASA. This medication is especially critical for patients managing conditions like **ulcerative colitis**.
Brand Names and Forms Available
In Canada, Mesalazine is found under the brand names **Asacol** and **Asacol HD**. These formulations come as delayed-release tablets available in two strengths: **400 mg** and **800 mg**. Moreover, there are rectal formulations such as enemas and suppositories offered by various competitive brands.
Medicinal Classification and ATC Code
Asacol falls under the **ATC Code** A07EC02, which denotes it as an anti-inflammatory medication specifically targeted for treating inflammatory bowel diseases. This classification confirms its role in addressing ailments such as ulcerative colitis.
Manufacturers and Registration
The **manufacturers** of Asacol include notable companies such as **Allergan** from the U.S., **Tillotts Pharma** from Switzerland, and **Meda Pharma** from Europe. Additionally, local generic versions are distributed across Canada through various licensing agreements. Asacol has successfully received approval from **Health Canada**, the **U.S. Pharmacopeia (USP)**, and the **European Medicines Agency (EMA)**, validating its use for ulcerative colitis treatment.
Prescription Status of Asacol
It's important to note that Asacol is classified as a **prescription medication (Rx)**, meaning it is not available over the counter (OTC). This classification is based on the need for professional supervision and safety considerations inherent in its use.
Dosage & Administration for Asacol
The correct dosage of Asacol is crucial for managing ulcerative colitis effectively. Patients often wonder how much to take for the best results. Knowing the right doses can play a big role in treatment success.
Typical Dosages
For adults dealing with active ulcerative colitis, the standard dosage generally falls between 2400 mg to 4800 mg daily. This is typically divided into three doses of 800 mg each.
Pediatric dosages depend on weight, usually ranging from 50 to 75 mg per kilogram of body weight, and should also be split into multiple doses throughout the day.
Adjustments for Comorbidities
When it comes to comorbidities, especially renal impairment, dosage adjustments may be necessary. It's essential to note that Asacol is contraindicated in individuals with severe renal dysfunction, posing potential risks.
Treatment Duration
Starting treatment usually involves an induction phase lasting around 6 to 8 weeks to address acute symptoms. Once stabilized, maintenance treatment often continues at a range of 1.6 g to 2.4 g per day, with regular assessments to determine its necessity.
Storage Guidelines
For optimal storage, Asacol tablets should be kept at temperatures between 15 to 30°C. It is also important to protect them from moisture and sunlight exposure.
Transporting Your Medication
When transporting Asacol, it is advisable to maintain it in its original packaging. Additionally, ensure it remains out of children’s reach to prevent accidental ingestion.
Safety & Warnings for Asacol
Understanding safety and warnings associated with Asacol is essential for all potential users. Patients often have concerns regarding possible side effects and contraindications.
Contraindications
It is absolutely contraindicated for anyone who has a known allergy to mesalazine or aspirin. Moreover, those with severe renal impairment should avoid Asacol due to the potential risk of exacerbating their condition.
Side Effects
Common side effects experienced include:
- Headaches
- Nausea
- Abdominal pain
More moderate concerns could involve renal dysfunction or allergic reactions. In rare instances, severe effects can arise, including acute interstitial nephritis or pulmonary reactions.
Special Precautions
For patients with pre-existing liver or kidney conditions, careful monitoring is critical. This ensures any adverse effects can be managed promptly.
Black Box Warnings
Currently, Asacol does not carry any black box warnings. However, ongoing monitoring is recommended, especially for those with a history of prior hypersensitivity to similar medications.
Patient Experience with Asacol
When considering a new treatment like Asacol, potential users often turn to reviews and shared experiences. This can provide insights into what to expect during their treatment journey.
Reviews
User experiences reported on platforms such as Drugs.com reveal a mix of feedback, highlighting varying degrees of effectiveness, especially in the relief of symptoms.
Feedback from Reddit and WebMD shows users experiencing everything from complete lack of symptoms to facing occasional side effects.
User Insights
Discussions on English-speaking forums, including Facebook groups, frequently touch on issues of adherence to medication. Many patients link their ongoing commitment to perceived side effects and the overall improvement of their condition.
Effectiveness
Many users note a significant positive impact on their ulcerative colitis flare-ups. However, individual responses can vary notably, often influenced by personal health factors.
Adherence Challenges
Adherence can become a challenge due to the pill burden alongside the perceived side effects. Regular check-ins with healthcare providers can help address concerns and support ongoing treatment.
Common Alternatives in Canada
When looking for alternatives to Asacol, individuals in Canada often explore several options. Each medicine has unique benefits and formulations that cater to similar conditions associated with ulcerative colitis and other inflammatory bowel diseases.
- Pentasa: This is an extended-release mesalazine option that provides targeted relief. It works well for individuals experiencing long-term treatment needs.
- Salofalk: Renowned for its versatility, Salofalk comes in many formulations, including granules and rectal preparations, catering to diverse patient preferences.
- Mezavant: Another extended-release option, known for its once-daily dosing, which simplifies medication management for users.
Comparison Table
It's essential to weigh options when considering alternatives to Asacol. Here's a concise view of how these medications stack up against each other based on key factors:
| Medication | Price (CAD) | Efficacy | Safety Profile | Availability |
|---|---|---|---|---|
| Asacol | $xx | Moderate to High | Common side effects | High |
| Pentasa | $xx | High | Similar to Asacol | Moderate |
| Salofalk | $xx | High | Varies by formulation | High |
Preferences
Among healthcare professionals, there’s a marked preference for Asacol. Many local doctors trust it for its consistent capability to manage ulcerative colitis effectively. Clinical guidelines often highlight Asacol's reliability, making it a go-to choice for numerous patients.
