Acticin
Acticin
- In our pharmacy, you can buy Acticin with a prescription, available in the Canada, Canada, and various other markets.
- Acticin is used for the treatment of scabies and lice infestations. The drug acts as a scabicide and insecticide by disrupting the function of the nervous system in ectoparasites.
- The usual dosage for scabies is to apply a thin layer to the entire body from neck down for 8–14 hours, usually as a single application, with possible repetition after one week if needed.
- The form of administration is a topical cream.
- The effect of the medication begins within a few hours after application.
- The duration of action is approximately 7 days, with potential re-application if needed.
- Avoid consuming alcohol while using this medication to prevent increased side effects.
- The most common side effects include mild skin reactions such as burning, stinging, itching, redness, and swelling.
- Would you like to try Acticin without a prescription?
Basic Acticin Information
- INN (International Nonproprietary Name): Permethrin
- Brand Names Available in Canada: Acticin, Elimite
- ATC Code: P03AC04
- Forms & Dosages: Cream (5%), lotion (1% for head lice)
- Manufacturers in Canada: Actavis Pharma (Teva) and various generics
- Registration Status in Canada: FDA-approved in the USA (Rx), Health Canada approved (Rx)
- OTC / Rx Classification: Prescription only for scabicide; some lice products may be OTC
What Is Permethrin?
Permethrin is the active ingredient in several topical treatments for skin infestations. It's known for its effectiveness against pests like scabies and head lice.
Brand Names in Canada
In Canada, you can find Permethrin under brand names like Acticin and Elimite. Both of these options contain a concentration of 5% permethrin and are mostly used to treat scabies—a condition caused by tiny mites that infest the skin.
Dosage Forms and ATC Code
The standard dosage forms of Permethrin include:
- Cream (5% for scabies)
- Lotion (1% primarily for head lice)
The ATC code for this medication is P03AC04. This classification falls under ectoparasiticides, indicating its use in treating infestations caused by parasites.
Manufacturers
Permethrin is produced by various manufacturers. In the USA, Actavis Pharma, now part of Teva, is among the notable producers. In Europe, it is marketed by companies like Omega Pharma, Ratiopharm, and Sandoz, which help ensure its availability across multiple markets.
Regulatory Status
Health Canada has approved Permethrin for prescription use, ensuring that it meets safety and efficacy standards. Similarly, it has received FDA approval in the USA. However, while Permethrin cream is available by prescription, some lice treatments containing a lower concentration may be obtained over-the-counter (OTC).
OTC and Prescription Classification
When considering treatment options, it’s essential to note that Permethrin, in its scabicide formulation (5%), is only available by prescription. Some stronger lice products may have OTC availability depending on the brand and formulation. Always consult with a healthcare provider to choose the right option for your specific situation.
Safety & Warnings
When considering Acticin, it's crucial to understand the safety and warnings associated with its use. This medication is primarily indicated for treating scabies and is effective, but there are certain precautions.
Contraindications
- Absolute: Those with hypersensitivity to permethrin or any active ingredient. Individuals with known allergies to chrysanthemums should avoid this medication.
- Relative: Caution is advised for patients with extensive skin conditions such as severe eczema or psoriasis, as these conditions may increase the risk of adverse effects.
Side Effects
As with any medication, side effects can occur. The most prevalent reactions include:
- Common: Itching, redness, and tingling at the application site.
- Rare: Severe allergic reactions or headaches.
It's important to report any severe reactions to a healthcare provider immediately.
Special Precautions
For those with liver or kidney impairment, monitoring is essential. Consultation with a healthcare provider is recommended if pregnant or breastfeeding to ensure safety for both the mother and child.
Black Box Warnings
Currently, no black box warnings are associated with Acticin.
Patient Experience
Understanding how individuals experience Acticin can provide valuable insights. Reviews from websites like Drugs.com and WebMD generally highlight its effectiveness in treating scabies. Users report noticeable relief after application, citing the ease of use as a benefit.
User Feedback from Online Forums
On platforms such as Reddit, many users share experiences regarding adherence to treatment plans and side effects. While most find the treatment effective, there are occasional mentions of discomfort during application.
Subjective Insights
Effectiveness can vary depending on the underlying conditions of the patient. While many see fast improvement, some report that it takes longer for others to notice significant changes. This variability highlights the importance of individualized care and open communication with healthcare professionals.
Alternatives & Comparison
Acticin is a popular choice for treating scabies, but alternatives exist. In Canada, treatments like Crotamiton (Eurax) and Lindane are available. However, Lindane is often avoided due to its neurotoxic potential.
Comparison Table
| Brand | Type | Effectiveness | Safety | Availability |
|---|---|---|---|---|
| Acticin | Cream | Highly effective for scabies | Good | Rx only |
| Elimite | Cream | Similar to Acticin | Good | Rx only |
| Nix | Lotion | Effective for head lice | Safe for kids | OTC |
Local physicians may prefer Acticin or Elimite for scabies due to their proven effectiveness and safety profiles, while Nix is commonly chosen for head lice due to its over-the-counter availability.
Market Overview
Acticin's availability can be quite straightforward. It's often found in pharmacies like Catena and PharmaChoice, making it accessible for patients needing treatment for scabies.
Average Price
The average price for Acticin in Canada typically ranges around CAD, offering a cost-effective solution for patients dealing with scabies.
Packaging
Acticin usually comes in 30g and 60g tubes, providing options based on patient needs. The off-white cream base is designed for easy application and absorption into the skin.
Demand Patterns
Seasonal trends indicate a spike in the use of scabicides like Acticin during warmer months when activities increase, leading to higher rates of skin infestations. Awareness campaigns and educational efforts are crucial to managing demand effectively.
Research & Trends on Acticin
In the past few years, several clinical trials focusing on permethrin, the active ingredient in Acticin, have provided valuable insights into its effectiveness and potential uses. A recent meta-analysis published in 2023 reviewed multiple studies and reaffirmed permethrin’s status as a first-line treatment for scabies, confirming its high efficacy rates when applied as directed. Trials conducted in 2022 to 2025 have also explored permethrin’s effectiveness in treating other ectoparasitic conditions.
Beyond its traditional uses, research has indicated potential extended applications of permethrin. Some studies are investigating its role in treating resistant strains of head lice, leading to hopes of broader uses in ectoparasitic treatments. Preliminary findings suggest that permethrin could also play a role in addressing certain insect-borne diseases.
The patent status of Acticin remains strong internationally, as patents protect its formulation in many jurisdictions. However, generics of permethrin cream are now available in Canada, providing more accessible options for patients. These generics maintain compliance with Health Canada’s requirements, ensuring quality and safety.
Guidelines for Proper Use of Acticin
For optimal results with Acticin, adhering to specific guidelines is crucial. Apply the cream as directed by your healthcare provider, ensuring a thorough coating on clean, dry skin. Typically, a thin layer should be spread over the entire body from the neck down, and the treatment should be left on for 8 to 14 hours before washing it off.
Avoid common pitfalls such as:
- Mixing with alcohol or other topical treatments, which can lead to reduced effectiveness.
- Neglecting to apply to the entire body, especially for scabies.
- Failing to wash off the cream after the specified time, which can compromise treatment effectiveness.
Lastly, ensure proper storage at room temperature, away from moisture and extreme heat. Consulting the patient leaflet for detailed instructions is always recommended to enhance treatment adherence and safety.